摘要
目的：观察新疆阿尔泰人工虫草菌丝体（ＣＣＭ）及培养液（ＣＣＬ）的护肝作用。方法：采用Ｄ－氨基半乳糖（Ｄ－Ｇａｌ）致大鼠小鼠实验性肝损伤。结果：ＣＣＭ及ＣＣＬ灌胃可使小鼠肝损伤升高的血清谷丙转氨酶及谷草转氨酶明显下降（Ｐ＜０．０５），而对大鼠肝损伤升高的谷丙转氨酶及谷草转氨酶作用不明显（Ｐ＞０．０５），但可使大鼠肝损伤升高的血清前白蛋白明显下降（Ｐ＜０．０５）。病理组织切片显示，ＣＣＭ和ＣＣＬ对大鼠及小鼠肝损伤的肝组织均有一定的保护作用。
Aim:to observe the protective effect of artifical mycelia of cultivated cardyceps(CCM) and cultivated liquid(CCL) from xinjiang altai district.Method:The D galactosamine(D Gal) was used for rats and mice experimental hepatic injury.Result:The experiment showed that CCM and CCL could obviously reduce the rising serum alanine transaminase and serum glutamic oxaloacetic transaminase from the hepatic injury in mice( P < 0.05 ),but there was no obvious effect on rising alanine transaminase and glutamic oxaloacetic from the hepatic injury for rats( P > 0.05 ).However,CCM and CCL could reduce the prealbumin rose from hepatic injury for rats( P < 0.05 ).Conclusion:The pathology cut section shows that CCM and CCL have certain protective effect for rats and mice,which suffered hepatic injury from D Gal.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1998年第11期488-490,共3页
Chinese Journal of Hospital Pharmacy
关键词
人工虫草
菌丝体
培养液
肝损伤
D-GAL
mycelia of cultivated cardyceps cultivated liquid
D galactosamine
hepaticinjury
