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HIV-1潜伏库研究进展 被引量：8

Progresses in the Mechanism of HIV-1 Latency Formation
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摘要 HIV-1在未经治疗的艾滋病患者体内虽可以持续复制,但也可潜伏在细胞内以逃避宿主的免疫清除,这一现象即病毒潜伏。病毒潜伏对抗病毒治疗带来了挑战,也引起人们的高度关注。本文对HIV-1病毒潜伏库的研究进展进行了综述。 Although HIV-1 can replicate continuously in untreated patients, they can also be hidden intracellularly to evade the host immune clearance, that is latent virus. As the viral latency is a challenge to antiviral treatment, great concern has arisen. This article reviews literature on the mechanism of HIV-1 latency formation.
作者 焦艳梅 吴昊
机构地区 首都医科大学附属北京佑安医院感染科
出处 《首都医科大学学报》 CAS 北大核心 2009年第5期639-642,共4页 Journal of Capital Medical University
基金 国家"十一五"传染病重大专项(2008ZX10001-006) 国家重点基础研究发展计划项目(2006CB504201) 北京市科委重大项目(D09060030405912)资助项目~~
关键词 病毒DNA 潜伏 HIV-1潜伏库 virus DNA latency latency formation of HIV-1
分类号 R512.91 [医药卫生—内科学]
  • 相关文献

参考文献26

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二级参考文献22

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共引文献6

同被引文献97

  • 1杨文万,石鸥燕,张菊芳.主成分分析在基因表达谱数据分析中的应用[J].包头医学院学报,2005,21(4):435-436. 被引量：2
  • 2蒋卫民,卢洪洲,潘孝彰.HIV潜伏感染的细胞和分子机制[J].中国艾滋病性病,2006,12(1):78-80. 被引量：8
  • 3谢静,李太生.清除体内潜伏感染人类免疫缺陷病毒的新策略[J].中华医学杂志,2006,86(48):3450-3452. 被引量：7
  • 4王成雄,饶妮妮,王玉.用主成分分析探索基因表达模式[J].生物医学工程学杂志,2007,24(4):736-741. 被引量：2
  • 5Tingting Du Phillip D Zamore.Beginning to understand microRNA function[J].Cell Research,2007,17(8):661-663. 被引量：20
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引证文献8

二级引证文献9

首都医科大学学报
2009年 第5期

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