摘要
固相有机合成是组合化学中构建化合物库的主要工具之一［１，２］，但是，由于它是连接在固相载体（如树脂等）上的试剂与溶解在有机溶剂中的试剂之间的反应，因此反应比较缓慢．考虑到微波技术对有机反应的协助作用，我们将微波技术应用到固相有机反应中，对比研究了微波...
Microwave assisting the addition reaction of Wang resin bound secondary amine 1 and isocyanate was carried out for the first time. The reaction time course was determined by analyzing FTIR spectra obtained using the improved KBr pellet method by grinding down the resin beads prior to recording. The results showed that the reaction assisted by microwave was accomplished only in 12 min, while the reaction without microwave was completed in 210 min.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1998年第10期1608-1610,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
微波
树脂
固相有机合成
仲胺
异氰酸酯
加成
Solid phase organic reaction, Microwave irradiation, FTIR, Resin beads
