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吡格列酮对2型糖尿病患者C反应蛋白的影响 被引量:2

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摘要 目的:观察吡格列酮治疗2型糖尿病(T2DM)前后血清高敏C反应蛋白(hs-CRP)的变化。方法:采用随机、双盲、安慰剂平行对照法将140例已合用磺脲类和双胍类药物的T2DM患者随机分为治疗组和对照组,治疗12周。结果:对照组的HbA1c明显下降(P<0.05),其他指标无显著变化;治疗组与治疗前比较FPG、2hPG、HbA1c、胰岛素抵抗指数、hs-CRP均明显下降(P<0.01)。结论:吡格列酮治疗T2DM,除能改善胰岛素抵抗,降低血糖,还有明显的抗炎作用,使hs-CRP下降。
作者 张秉涛
出处 《中国误诊学杂志》 CAS 2009年第28期6846-6847,共2页 Chinese Journal of Misdiagnostics
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