摘要
目的:探讨缬沙坦对原发性高血压伴尿微量白蛋白的影响。方法:选择110例原发性高血压伴尿微量白蛋白的患者,采用对照法比较,观察缬沙坦治疗12周血压和24h尿微量白蛋白的变化。结果:治疗后患者血压和24h尿微量白蛋白较前显著下降,差异有统计学意义。结论:缬沙坦能有效降压并改善早期肾功能损害。
Objective： To observe the effects of losartan on the microalbuminuria in patients with essential t hypertension. Methods： One hundred and ten patients with primary hypertension with microalbuminuria were ran- domized into groups of therapy（n=56） and controls（n=54）.After12 weeks of medication with losartan ,two groups of patients were compared regarding the variation of blood pressure and 24 hours microalbuminuria levels. Results： The 24 hours microalbuminuria levels and blood pressure were decreased significantly in patients with medication of losartan as compared with their previous and the two groups were different statistically. Conclusion： losartan can effectively reduce the blood pressure and protect the renal function from early impairment.
出处
《安徽卫生职业技术学院学报》
2012年第4期51-51,90,共2页
Journal of Anhui Health Vocational & Technical College
关键词
高血压
24h尿微量白蛋白
缬沙坦
临床观察
Hypertension
24 hours microalbuminuria
Losartan
Clinical observation
