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急性冠脉综合征患者血清缺血修饰白蛋白的变化及其临床意义 被引量：2

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摘要 目的探讨急性心肌梗死（AMI）和不稳定性心绞痛（UA）患者血清缺血修饰白蛋白（IMA）的变化及其临床意义。方法测定80例急性冠脉综合征（ACS）患者（AMI42例、UA38例）和29例非冠心病者（对照组）血清IMA。ACS患者按临床谱、冠脉病变数和Gensini积分不同进行分组。UA和非ST段抬高性心肌梗死（NSTEMI）患者按危险性分层进行分组。分析不同组ACS患者血清IMA的差异。结果UA组和AMI组患者血清IMA值均显著高于对照组，UA组与AMI组间血清IMA值无差异；冠脉单支病变组血清IMA值显著低于冠脉三支病变组；冠脉Gensini积分〈20分组血清IMA值显著低于〉40分组；UA和NSTEMI患者低危组血清IMA值显著低于高危组。结论IMA有可能作为诊断无心肌细胞坏死急性心肌缺血和反映心肌缺血严重程度的标记物。
作者 安亚平 刘志琴 黄山
机构地区 贵州省人民医院心内科 贵州省检验中心
出处 《临床内科杂志》 CAS 2009年第9期626-628,共3页 Journal of Clinical Internal Medicine
基金 贵州省优秀科技人才省长转项资金项目（200607）
关键词 急性冠脉综合征 急性心肌梗死 不稳定性心绞痛 缺血修饰白蛋白
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献10

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同被引文献16

  • 1张妍,周玉杰,谢英,李艳芳,赵迎新,刘宇扬,梁静.TC/HDL-C与hs-CRP的检测在冠心病诊断中的意义[J].中国医师进修杂志（内科版）,2006,29(6):28-30. 被引量：6
  • 2中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量：5227
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  • 9Ju SQ,Ni J,Su JY,et al.Ischemia-modified albumin is increased in patients with unstable angina:a new potential diagnostic biomarker of this acute coronary syndrome[J].LabMediscine,2008,39(11):668-670.
  • 10Shen XL,Lin CJ,Han LL,et al.Assessment of ischemia-modified albumin levels for emergency room diagnosis of acute coronary syndrome[J].Int J Cardiol,2011,149(3):296-298.

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临床内科杂志
2009年 第9期

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