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葡萄球菌属医院感染的耐药现状调查分析 被引量:13

Drug-Resistance of Staphylococcus in Nosocomial Infection
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摘要 目的了解葡萄球菌属医院感染和耐药现状,以采取有效措施控制医院感染。方法采集2006年1月-2008年12月医院感染患者临床各类标本中分离的葡萄球菌属129株,对其进行细菌鉴定、耐甲氧西林葡萄球菌(MRS)检测和K-B法药敏试验,并进行统计与分析。结果129株葡萄球菌属分为6种,以金黄色葡萄球菌(SAU)分离率最高,为39.5%,其中耐甲氧西林金黄色葡萄球菌(MRSA)占29.4%,凝固酶阴性葡萄球菌(CNS)分离率为60.5%,其中耐甲氧西林药凝固酶阴性葡萄球菌(MRCNS)占32.1%;药敏结果显示甲氧西林敏感葡萄球菌(MSS)耐药率明显低于耐甲氧西林葡萄球菌株。结论基层医院耐甲氧西林葡萄球菌医院感染比较严重,应采取有效措施,控制耐甲氧西林葡萄球菌医院感染。 OBJECTIVE To study drug-resistance status in nosocomial infection with Staphylococcus in the local region, and take effective measures to control the nosocomial infection. METHODS Totally 129 strains of Staphylococcus were clinically isolated from various specimens from Jan 2006 to Dec 2008. The strain identification, detection of meticillin-resistant Staphylococcus (MRS) and K-B disk diffusion test were performed. The data were analyzed statistically. RESULTS Among all 129 strains consisting of 6 species of Staphylococcus, the isolating rate of S. aureus predominated with 39. 5%. Among them, meticillin resistant S. aureus (MRSA) accounted for 29.4 %. Among all coagulase-negative Staphyloccocus(CNS), meticillin-resistant coagulase-negative Staphylococcus (MRCNS) accounted for 32.1%. Meticillin-susceptible S. aureus (MSSA) showed significantly lower drugresistance than MRS. CONCLUSIONS Nosocomial infection status caused by MRS is serious in the grass-roots hospitals. Effective measures should be taken to control it.
作者 陈经艾 涂斌
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2009年第16期2181-2182,共2页 Chinese Journal of Nosocomiology
关键词 葡萄球菌属 医院感染 耐药性 监测 Staphylococcus Nosocomial infection Drug-resistance Monitoring
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