摘要
目的 研究原发性肺癌与性激素受体的关系。方法 应用免疫组化SP法对47例患者进行雌激素受体（ER），孕激素受体（PR）及雄激素受体（AR）检测。结果 原发性肺癌的ER、PR及AR阳性率分别为65．95％、61．70％及61．70％。结论 本结果显示肺癌与性激素受体有一定关系，肺癌细胞分化程度越高，性激素受体阳性率越高。通过检测了解肺癌生物学特性，提示内分泌治疗对肺癌性激素受体阳性患者有效，并对预测其预后有一定意义。
In this paper, we investigated the presence of estrogen (ER), progesterone (PR) andandrogen (AR) receptors in 47 cases of the primary lung carcinoma using immllnohistochemistry SPmethod. The results showed that the positive rates of ER, DR and AR were 65. 95％, 61. 70％ and 61.70％ respectively. The primary lung carcinomas are related to the steroid hormones. The better differ- entiation of the cancer cell, the higher positive rate of the steroid hormones. By examining steroid hor- mone receptors, we could make a better understanding of the biological characters of the lung carcino-ma. It was concluded that anti-steroid therapy may be helpful for the patients with positive steroid hor- mone receptors and the steroid hormone receptor may be a good prognostic factor.[
出处
《中国肿瘤临床与康复》
1998年第2期16-17,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
原发性
肺癌
免疫组化
性激素受体
primary lung carcinonla, immunohistochemistry, ER:DR:AR
