摘要
【目的】为了了解广州地区变应性鼻炎主要吸入性变应原。【方法】采用德国敏筛(Allergyscreen)变应原检测系统,检测我院变应性鼻炎患者常见吸入性特异性IgE和总IgE含量,并将患者分成未成年组(≤18岁)和成年组(>18岁),回顾性分析我院不同年龄变应性鼻炎患者常见吸入性变应原特异性IgE阳性率及其分布差异。【结果】625例变应性鼻炎患者中吸入性变应原特异性IgE阳性率依次为尘螨84.32%、蟑螂19.04%、柏树15.20%、动物毛皮屑组合13.12%、树木花粉组合7.20%、矮豚草5.12%,葎草1.76%、蒿草1.76%、霉菌组合1.44%;总IgE阳性者413例(66.1%)明显低于特异性IgE阳性率;两组中最常见的变应原相似;未成年组屋尘螨的阳性率及敏感程度明显高于成年组(P<0.01)。【结论】①我院变应性鼻炎患者最主要的吸入性变应原是屋尘螨、蟑螂、柏树、动物毛皮屑,可为广州地区参考;②未成年人对尘螨过敏的比例及敏感程度均高于成年人。
[Objective] To study the aeroallergens in the patients with allergic rhinitis in Guangzhou. [Methods] Using the German screen allergens quantitative detection system to determinate serum aeroallergen specific IgE and total IgE levels of 625 cases with allergic rhinitis diagnosed in The Third Hospital of SUN Yat-sen University. Tile samples were stratified on two age groups： the juvenile and the adult. Difference of serum aeroallergen specific IgE of the two groups was investigated. [Results] Aeroallergen specific IgE antibody in the serum of 625 patients with allergic rhinitis were positive. Total IgE in serum was positive in 413 cases, accounting for 66.1%. The positive rate of total IgE was less than that of aeroallergen specific lgE. The positive rate of aeroallergen specific IgE in order were mite mixture （84.32%）, cockroach （19.04%）, cypress （15.20%）, cat-dog epithelia （ 13.12% ）, tree mixture （7.20%）, ragweed （5.12%）, humulus lupulus （ 1.76% ）, mugwort （ 1.76% ）, mould mixture （1.44%）. In the two groups, the positive rate of aeroallergen specific IgE in order were similar. There were significantly higher sensitivity and positive rate of mite mixture in the juvenile group than the adult group （P 〈 0.01）. [Conclusion] The most important aeroallergens are mite mixture, cockroach, cypress, cat-dog epithelia, which could be referenced as Guangzhou patients . The juvenile is more sensitive to mite than the adult.
出处
《中山大学学报（医学科学版）》
CAS
CSCD
北大核心
2009年第4期446-449,共4页
Journal of Sun Yat-Sen University:Medical Sciences
基金
广东省医学科研基金(B2008051)
