摘要
目的探讨末梢全血CRP测定在儿童急性感染疾病中应用价值。方法256例急性感染儿童治疗前分别测定末梢全血CRP、WBC计数值及抗生素治疗72h后的末梢全血CRP、WBC计数值,以50例健康体检儿童为对照。结果细菌感染组CRP和WBC均明显升高,与正常对照组比较,t检验也有显著性差异(p<0.05);病毒感染组无显著性差异(p>0.05);细菌感染组198例患儿血CRP值增高,CRP阳性率88%,WBC测定阳性有95例,阳性率42%,两者2检验有显著性差异(p<0.05);198例CRP增高的儿童进行抗生素治疗72h后,末梢全血CRP明显下降,与治疗前相比,t检验也有显著性差异(p<0.05),WBC计数只有轻度下降,与治疗前相比,t检验无显著性差异(p>0.05)。结论末梢全血CRP的测定具有快速准确、灵敏度高、所用标本量少的特点,是诊断儿童急性感染疾病时区别细菌和病毒感染的重要指标,在临床上的用药及疗效观察上有重要的临床应用价值。
Objective To discuss the value of CRP detection by peripheral whole blood in diagnosis of children＇ s acute infectious disease. Methods The level of CRP（ serum and whole blood） and white blood cell（WBC） counts of 256 patients suffering from acute infections were detected before treatment and after antibiotic treatment for 72 h respectively, 50 children of normal health examination were selected as a control group Results The level of CRP and WBC in bacteria infection group increased significantly, compared with the normal control group （p 〈 0. 05 ） ,the level of CRP and WBC in viral infection group had no significant difference（p 〉0. 05）,the level of CRP in 198 cases of bacteria infection group was increased, the positive rate of CRP was 88%, the level of WBC in 95 cases was positive, the positive rate of 42%, whichever in ;χ^2 test were significantly different（p 〈 0. 05 ）. The level of CRP in 198 cases of children was obviously reduced 72 hours after treatment with antibiotics, showing difference （p 〈 0. 05 ）, while WBC mild decline after treatment and no significant different （p 〉 0. 05 ）. Conclusion The CRP detecting with peripheral blood, which characterized by rapid, accuracy, high sensitivity, and less specimen is an important indicator for the bacterial and viral infection of children＇s acute infectious disease. It has the clinical value in the drug -using and therapeutic observation.
出处
《现代医院》
2009年第8期73-74,共2页
Modern Hospitals
