摘要
研究预防性给予中药复方制剂降粘抗栓片Ⅰ(JNKST.Ⅰ)号对Sprague-Dawley大鼠实验性高脂血症的影响.方法:用Sprague-Dawley大鼠作为实验对象,连续喂饲高脂饲料2wk,复制高脂血症模型;同时用JNKST.Ⅰ灌胃,第15日测定血清血脂.结果:JNKST.Ⅰ能明显降低血清TC,LDL-C水平及TC/HDL-C比值(P<0.01).结论:JNKST.Ⅰ能调节血脂,可用于防止高脂血症.
Aim:To observe the effects of the suspension ofJiangnian Kangshuan Tablet No.Ⅰ (JNKST.Ⅰ), on the experimental hyperlipemia in rats. Methods: Rats fed with alipid-rich diet for 2 wk and the mimic model of hyperlipemiawas then established; at the same time the JNKST.Ⅰ wasgiven to the rabbit by gastrogavage and blood lipid was detected on the 15th day. Results: The tablet reduced theserum of total cholesterol (TC), low-density lipoproteincholesterol (LDL-C) and the ratios of TC to high-densitylipoprotein cholesterol (TC/HDL-C) (P<0. 01 ). Conclusion: JNKST.Ⅰ is effective for reducing hyperlipemia. Theresults indicated that the JNKST.Ⅰ could be used to preventhyperlipemia.
出处
《第四军医大学学报》
1998年第4期391-393,共3页
Journal of the Fourth Military Medical University
基金
陕西省重点科研项目!97k12-G5
关键词
降粘抗栓片I号
高脂血症
中医药疗法
Jiangnian Kangshuan
Tablet No.Ⅰ
hyperlipemia
herb drugs
rat