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食管癌中^18F-氟脱氧葡萄糖摄取和葡萄糖转运蛋白1表达的相关性研究

Research of the relationship between expression of glucose transporter-1 and ^18F-fluorodeoxyglucose uptake in esophgeal cancer
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摘要 食管癌的发生和发展涉及多个基因、分子水平的异常,是多个因素参与、共同作用的结果。^18F-氟脱氧葡萄糖(^18F-FDG)PET检测肿瘤细胞糖摄取在肿瘤诊断、分期、疗效评价、预后判断等方面的应用越来越广泛,而葡萄糖转运蛋白1(Glut-1)在食管癌肿瘤细胞葡萄糖摄取和细胞增殖过程中起重要作用。 The occurrence and development of esophgeal cancer is a result of many factors that effect each other, which involved disorders of multiple genes and levels of molecular. The application of ^18F-fluorodeoxyglucose (^18F-FDG) PET detecting tumor cells glucose uptaked is more and more generally in the tumor diagnosis, staging, curative effect evaluation, and prognosis judgement and so on, glucose transporter-1 has an important role in the esophgeal cancer cells glucose uptaked and cells proliferation process.
出处 《国际放射医学核医学杂志》 2009年第1期18-21,共4页 International Journal of Radiation Medicine and Nuclear Medicine
关键词 食管肿瘤 氟脱氧葡萄糖F18 葡萄糖转运蛋白1 Esophgeal neoplasms Fluorodeoxyglucose F18 Glucose transport protein-1
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