期刊文献+

术后肠麻痹发病机制的研究进展 被引量:7

Advances in the mechanisms of postoperative ileus
原文传递
导出
摘要 术后肠麻痹通常指腹部手术后引起的胃肠运动功能的抑制。影响手术患者胃肠运动功能的因素是多方面的,如疼痛、手术操作和电解质平衡紊乱等。虽然多数患者症状较轻,胃肠运动功能常于术后短期内自行好转,但仍有少数患者胃肠运动紊乱的时间持续较长,治疗困难,由此加重病情,延长术后康复,延长住院时间以及增多治疗费用等。明确术后肠麻痹的病因和发病机制有助于对其进行防范和治疗。 Postoperative ileus is commonly referred to the inhibition of gastrointestinal motility after abdominal surgery. Some causes are responsible for the ileus, including postoperative pain and electrolyte imbalances, and manipulations during surgery. Although gastrointestinal motility normalizes spontaneously in most patients, some develop severe to postoperative ileus, which is difficult to treat,with a delayed recovery from surgery, prolonged hospital stay, and increased treatment costs. So, it is essential to understand the mechanisms of postoperative ileus for effective prevention and treatment.
出处 《国际外科学杂志》 2009年第5期319-322,共4页 International Journal of Surgery
基金 国家自然科学基金资助项目(No.30770978)
关键词 术后肠麻痹 胃肠运动 发病机制 postoperative ileus gastrointestinal motility mechanism
  • 相关文献

参考文献14

  • 1Lubawski J,Saclarides T.Postoperative ileus:strategies for reduction[J].Ther Clin Risk Manag,2008,4(5):913-917.
  • 2Bisanz A,Palmer JL,Reddy S,et al.Characterizing postoperative paralytic ileus as evidence for future research and clinical practice[J].Gastroenterol Nuts,2008,31(5):336-344.
  • 3Jottard K,Hoff C,Maessen J,et al.Life and death of the nasogastric tube in elective colonic surgery in the Netherlands[J].Clin Nutr,2009,28(1):26-28.
  • 4Mueller MH,Glatzle J,Kampitoglou D,et al.Differential sensitization of afferent neuronal pathways during postoperative ileus in the mouse jejunum[J].Ann Surg,2008,247(5):791-802
  • 5Lighffoot A J,Eno M,Khmer K J,et al.Treatment of postoperative ileus after bowel surgery with low-dose intravenous erythromycin[J].Urology,2007,69(4):611-615.
  • 6Trudel L,Bouin M,Tomasetto C,et al.Two new peptides to improve post-operative gastric ileus in dog[J].Peptides,2003,24 (4):531-534.
  • 7Lelievre V,Favrais G,Abaci C,et al.Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide:a model for the study of intestinal ileus and Hirschspmng's disease[J].Peptides,2007,28 (9):1688-1699.
  • 8Huizinga JD,Lammers WJ.Gut peristalsis is governed by a multitude of cooperating mechanisms[J].Am J Physiol Gastrointest Liver Physiol,2009,296(1):G1-8.
  • 9Kehlet H.Postoperative ileus-an update on preventive techniques[J].Nat Clin Pract Gastroenterol Hepatol,2008,5(10):552-558.
  • 10ngowska-Umer H,Umer A,Sein-Anand J,et al.Endothelin receptor blockers protect against ischemia/reperfusian impairment of gastrointostinal motility in rats[J].Pharmacol Res,2008,57 (6):413-418.

同被引文献45

引证文献7

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部