摘要
放免法测定４３例行大肠癌根治术患者空腹血清、癌组织及癌旁粘膜中胃泌素水平。结果：大肠癌患者空腹血清胃泌素水平明显高于正常血对照组（Ｐ＜０．０５）；根治术后却明显降低（Ｐ＜０．０５），且与血对照组比无显著性差异（Ｐ＞０．０５）。高分化腺癌组血清胃泌素水平变化明显；癌组织及癌旁粘膜中胃泌素水平均高于正常大肠粘膜（Ｐ＜０．０５）。本结果提示：胃泌素对大肠癌的生长可能有调控作用。
Gastrin(G) concentration in fasting blood, cancer tissues and its adjacent mucosas sampled from fourty three patients with large intestine carcinoma (LIC) were measured. The results showed fasting G levels in patients with LIC were significantly higher than those in the normal surum controls ( P <0.05),and dropped to normal value after resection of the cancers. Surum G levels were correlated with cell differentiations of the cancer.The cancer tissues and its adjacent mucosas contained higher levels of G than the normal mucosas ( P <0.05). The results provided a laboratory evidence that the growth of LIC in vivo were regulated by G and G level might be an indicative parameter for selection of patients with LIC to be treated with hormone therapy and the study of biological character of LIC.
出处
《中国普外基础与临床杂志》
CAS
1998年第1期16-18,共3页
Chinese Journal of Bases and Clinics In General Surgery
