摘要
目的探讨人类博卡病毒(HBoV)与儿童急性呼吸道感染(ARTI)的关系。方法RT-PCR检测2006年11月-2008年4月连续2个冬春季儿科418例呼吸道感染鼻咽分泌物标本的HBoV。结果HBoV阳性率为5.0%(21/418)。阳性者年龄在4月～5岁。下呼吸道感染HBoV阳性率11.1%(17/153)显著高于上呼吸道感染的1.5%(4/265)(χ2=18.741,P<0.001)。结论HBoV是本地区冬春季儿童呼吸道感染、尤其是下呼吸道感染的的重要病原之一。
Objective To investigate the prevalence of human bocavirus （HBoV） in children with acute respiratory tract infections （ARTI）. Methods HBoV was detected by reverse transcription polymerase chain reaction （RT-PCR） in nasopharyngeal swab samples from 418 pediatric patients with ARTI during 2 consecutive winter-spring seasons from December 2006 to April 2008 in Fuzhou area. Results Twenty-one of 418（5%） samples were positive for HBoV. All of the positive specimens were from children aged between 4 months and 5 years. The positive rate was significantly higher in lower respiratory tract infections than in upper respiratory tract infections （11. 1% vs 1.5%, χ^2 -= 18. 741, P〈0. 01）. Conclusion HBoV is an important pathogen in ARTI especially in lower respiratory tract infections in Fuzhou area.
出处
《福建医科大学学报》
2009年第2期159-162,共4页
Journal of Fujian Medical University
基金
福建省自然科学基金资助项目(F0310042)
关键词
呼吸道感染
急性病
聚合酶链反应
细小病毒B19
人
细小病毒科感染
福州
respiratory tract infections
acute disease
polymerase chain reaction
parvovirus B19, human
parvoviridae infections
Fuzhou
