期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

异丙酚对冠状动脉旁路术病人术前血流动力学的影响 被引量：7

The Hemodynamic Effects of Propofol in Patients Undergoing Coronary Artery Bypass Surgery
暂未订购
导出
摘要 目的和方法：对１９例择期冠状动脉旁路术病人麻醉诱导前各静注异丙酚１～２ｍｇ／ｋｇ（１．７ｍｇ／ｋｇ），观察其后２、４、８ｍｉｎ血流动力学效应。结果：用药后２ｍｉｎ平均动脉压（Ｐ＜０．００１）、肺动脉压（Ｐ＜０．００２）、外周血管阻力（Ｐ＜０．００１）、心每搏量（Ｐ＜０．０５）、每搏指数（Ｐ＜０．０２）和左心室搏出功指数（Ｐ＜０．００１）均比对照组降低非常显著；由于心率明显增快（Ｐ＜０．００１），故心输出量和心脏指数无改变。上述各血流动力学参数至４ｍｉｎ已恢复至对照值。结论：异丙酚扩张血管、降低外周阻力，从而短暂降低血压，用于冠状动脉旁路术的麻醉时，应依病人年龄、ＡＳＡ等选择剂量。 Objective and Methods:19 patients, scheduled for elective coronary artery bypass, received propofol 15～20mg/kg and 10～15mg/kg iv, respectively before anesthesia induction. The hemodynamic effects were observed at 2min, 4min and 8min after propofol. Results: Propofol caused a significant fall in MAP(P<0001), PAP(P<0002),SV(P<005), SI(001<P<002) and LVSWI (P<0001) at 2min after propofol, as compared with that in control group. There was no change in cardiac output(CO) or cardiac index(CI). This was largely due to an increase in HR. The hemodynamics returned to control values till 4min after propofol adminstration. Conclusion: Propofol may lead to transient lowering of blood pressure induced by lowered peripheral resistance.
作者 叶平安 白各庆
机构地区 西安医科大学第一附属医院麻醉科
出处 《临床麻醉学杂志》 CAS CSCD 1998年第2期85-86,共2页 Journal of Clinical Anesthesiology
关键词 异丙酚 冠状动脉旁路术 血流动力学 术前 Propofol Coronary artery bypass Hemodynamics
分类号 R654.205 [医药卫生—外科学] R971.2 [医药卫生—药品]
  • 相关文献

参考文献9

  • 1Paul-Micbel de Grood. Clinical eva1uation of propofo1, a new intravenous anaesthetic. Druk, SNN Nijmegen, 1987,33--130.
  • 2Greunds RM, Twigley AJ, Carli F, et al .The haemodynamic effects,of intravenous induction comparison of the effects of thiopentone and propofol.Anaesthesia,1985,40(8):735.
  • 3Claeys MA, Gepts E, Camn F. Haemodynamic changes during anaesthesia induced and maintained with propofol, Br J Anaesth,1988,60(1):3.
  • 4Lippmann M, Paicius R, Cingerich S, et al A controlled study of the hemodynamic effects of propofol vs thiopental anesthesia induction, Anesth Analg,1986,65(Suppl 2):89.
  • 5Lees NW, McCulloch M, Mair WB. Propofol ('Diprivan) for induction and maintenance of anaesthesia. Postgrad Med J, 1985,61(Suppl )3:88.
  • 6Patrick MR, Blair IJ, Feneck RO, et al. A comparison of the haemodynamic effects of propofol( 'Diprivan' )and thiopentone in patients with coronary artery disease. Ibid,1985,61(Suppl 3):23.
  • 7Vermeyen KM, Erpels FA, Janssen LA, et al .Propofol-fentanyl anaesthesia for coronary bypass surgery in patients with good left ventricular function. Br J Anaesth,1987,59(9):115.
  • 8Russell GN, Wright BL, Fox MA, et al. Propofolfentanyl anaesthesia for coronary artery surgery and cardiopulmonary bypass. Anaesthesia, 1989,44 ( 3 ):205.
  • 9Robinson FP, Dundee JW, Halliday NJ. Age alfects the induction of propofol ( 'Diprivan' ). Postgrad Med .J,1985,61(Suppl 3):157.

同被引文献18

  • 1王祥瑞 杭燕南.异丙酚的临床应用[J].麻醉与重症监测治疗,1996,2:57-58.
  • 2刘俊杰 赵俊.现代麻醉学[J].北京:人民卫生出版社,1991.223.
  • 3曾因明 应诗达 杭燕南.麻醉科手册[M].上海：上海科技出版社,1996.45.
  • 4Janssen PA. Potent, new analgesics, tailor-made for different purposes[J]. Acta Anaesthesiol Stand, 1982, 26(3) :262 - 268.
  • 5潘永泉 戴体俊 曾因明 应诗达 杭燕南主编.静脉全麻药[M].曾因明,应诗达,杭燕南主编.麻醉科手册[C].上海:上海科技出版社,1996.45.
  • 6刘俊杰 赵俊.现代麻醉学[M](第2版)[M].北京:人民卫生出版社,1991.318.
  • 7刘俊杰 赵俊.现代麻醉学[M].北京：人民卫生出版社,1991.213.
  • 8俞卫峰.麻醉与复苏新论（第1版）[M].上海:第二军医大学出版社,2001.569.
  • 9何德兰 李香莲.医护心理探讨[M].天津：天津科学技术出版社,1989.129.
  • 10刘俊杰,赵俊.现代麻醉学[M].第2版.北京:人民卫生出版社,1992,222.

引证文献7

二级引证文献24

临床麻醉学杂志
1998年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部