摘要
目的:观察分化型甲状腺癌并远处转移患者接受多次大剂量131I治疗的临床效果。方法:45例分化型甲状腺癌并远处转移患者,根据甲状腺癌转移部位给予患者每次口服131I(370～740)×107Bq,分2～8次用药,每2次间隔4～12个月;治疗后4～6个月,采用131I全身显像和血清甲状腺球蛋白评价治疗效果。结果:45例中临床治愈15例,有效26例,无效4例。结论:多次131I治疗分化型甲状腺癌转移灶疗效佳,副作用小。
Objective：To assess the effect of iodine-131 （ 131 I ） therapy on patients with differentiated thyroid carcinoma metastases. Methods ： Forty-five patients with differentiated thyroid carcinoma metastases were treated with 131I, and the dose of 1311 varied according to the site of metastasis（ 370 ×10^7 to 740 × 10^7 ） Bq. The therapy was repeated 2 to 8 times at an interval of 4 to 12 months. The efficacy was assessed 4 - 6 months later with 131I whole body scanning and serum level of thyroglobulin. Results： Of the 45 cases, 15 were cured,26 improved and 4 had no response. Conclusions： The therapy of high doses of 131I is safe and effective for treatment of differentiated thyroid carcinoma metastases with little adverse side-effect.
出处
《蚌埠医学院学报》
CAS
2009年第2期114-116,共3页
Journal of Bengbu Medical College
