摘要
目的通过建立松质骨挤压的动物模型,模拟临床种植体挤压植入术,测量骨形态计量学参数,观察松质骨挤压后愈合过程中骨小梁排列的变化,为骨挤压技术的使用和改进提供实验依据和支持。方法以犬股骨髁松质骨为挤压部位,选择敲击挤压法,使用自行研制的挤压器,按照不同的挤压程度进行逐级挤压、备洞,植入与种植窝直径相同的圆柱状纯钛种植体。按照不同观察时期(1、2、4、12周)处死动物,取材,制作Messon染色硬组织切片,采用Osteomeasure软件测量骨形态计量学参数。结果松质骨受挤压后,在一定时期内骨小梁数增多,骨小梁间距减小,骨小梁厚度基本不变。前两者改变在2周内的愈合期比较明显,从第4周开始,经过12周的愈合,各参数与对照组之间趋于一致。结论骨挤压技术在一定时期内能够提高种植窝周骨小梁的致密度,可能有益于提高种植体的初期稳定性。
Objective This study simulated clinical implant surgery using squeeze technique by establishing a rational animal model. To measure the morphologic parameters in order to observe the agglutination of the cancellous bone after being compressed. The study wanted to get some favourable support of implant squeeze technique in bone healing and obtaining primary stabilities of implants, so as to provide some reasonable and valid guidance in the application and improvement of implant squeeze technique. Methods The cancellous bone in condyles of femur of dog had been chosen as the experimental position, prepared the implant holes using squeeze technique according to different compressing extent （0, 0.6, 1.2, 2.0 mm）, and then inserted the corresponding implants into them. After different healing periods （1, 2, 4, 12 weeks）, the mongerl dogs were sacrificed and the hard tissue slices were made and then the morphologic parameters were measured. Results The morphologic parameter of the bone tissue shows that after being compressed, the trabecular bone thickness was almost constant, while the trabecular bone number increased, and the trabecular bone spacing decreased, obviously in the 1-week and 2-week groups. The differences went down gradually along with the extend of healing time. Conclusion The clinical implant surgery using squeeze technique can improve peri-implant bone density so it is good for obtaining primary stabilities of implants.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2009年第1期104-106,116,共4页
West China Journal of Stomatology
关键词
松质骨
骨挤压
骨组织形态计量学
cancellous bone
bone compressing
bone histomorphometry
