摘要
设计并合成了２个新的手性源Ｓ－（－）－α－取代－２－羟基－５－甲基苄胺，从该手性源合成了４个光活性铜络合物，考察了它们对苯乙烯、１，１－二苯乙烯和２，４－二甲基－２，５－己二烯的不对称环丙烷化反应的光学诱导活性．结果表明，由Ｓ－（－）－１－（２－羟基－５－甲基苯基）－２－甲基丙胺与２－羟基萘甲醛缩合而得到的Ｓｃｈｉｆ碱为配体的铜络合物的诱导活性最佳．
Four chiral copper(Ⅱ) complexes derived from two novel chiral compounds (S) (-) α substituted 2 hydroxy 5 methylbenzylamine were synthesized. All the complexes were used as catalysts in the asymmetric cyclopropanation reaction of styrene, 1,1 diphenylethylene and 2,5 dimethyl 2,4 hexadiene. It is found that the more effective catalysts are related to complexes with ligands prepared from optically active amine and 2 hydroxy 1 naphthylaldehyde.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1998年第4期568-571,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
手性
铜
配合物
不对称
环丙烷化
诱导
Optically active amine, Olefins, Copper complex, Asymmetric cyclopropanation
