摘要
目的了解多药耐药铜绿假单胞菌消毒剂-磺胺耐药基因(qacE△1-sull)的存在状况。方法采用纸片扩散(K—B)法测定某院临床标本分离的30株铜绿假单胞菌对15种抗菌药物的敏感性;以聚合酶链反应(PCR)法检测qacE△1-sull基因。结果30株多药耐药铜绿假单胞菌中,qacE△1-sull基因阳性13株,阳性率43.33%。结论临床分离的铜绿假单胞菌qacE△1-sull基因携带率较高,应引起高度重视。本结果为山东地区首次报道。
Objective To study the qacE△1-sull gene in multiply drug-resistant Pseudomonas aeruginosa. Methods The susceptibility of 30 strains of clinical isolated Pseudornonasaeruginosa to 15 antirnicrobial agents was tested by Kirby-Bauer method,and qacE△1 -sull gene was analyzed by PCR. Results In 30 strains of Pseudomonas aeruginosa, the positive rate of qacE△1-sull gene was 43. 33% (13/30). Conclusion There is higher positive rate of qacE△1-sull gene in Pseudamonas aeruginosa isolated from the inpatients, it is reported for the first time in Shandong provine.
出处
《中国感染控制杂志》
CAS
2009年第1期7-9,20,共4页
Chinese Journal of Infection Control
基金
山东省科学技术发展攻关项目(2008GG10002040)