摘要
目的探讨临床分离的铜绿假单胞菌（PAE）耐药性和氯己定-磺胺耐药基因存在状况。方法采用PCR检测qacEΔ1-sull基因，测定临床分离的66株铜绿假单胞菌对6种抗菌药物的敏感性。结果66株PAE对6种抗菌药物的不敏感率在12．5％～87．5％之间，qacEΔ1-sull基因的阳性33株，阳性率50．0％。结论铜绿假单胞菌具明显的多重耐药特征，qacEΔ1-sull基因携带率很高。
OBJECTIVE To investigate the resistance of Pseudomonas aeruginosa isolated from two hospitals and its chlorhexidine-sulfadiazine-resistant genes （qacEΔ1-sull）. METHODS Microdilution tests were performed to detect the susceptibility of 66 strains of P. aeruginosa to 6 kinds of antimicrobial agents. The qacEΔ1-sull gene was analyzed by PCR. RESULTS The resistant rates to other antimicrobial agents were between 12.5-87.5%. qacEΔ1-sull gene was 50. 0%. CONCLUSIONS The 66 strains are multiple-drug-resistant. There are very high positive percentages of qacEΔ1-sull gene in P. aeruginosa isolated from two hospitals.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第2期137-138,142,共3页
Chinese Journal of Nosocomiology
关键词
铜绿假单胞菌
耐药基因
Pseudomonas aeruginosa
Resistance gene
