摘要
目的观察几种常用抗菌中药对耐甲氧西林金黄色葡萄球菌(MRSA)的抑菌活性。方法选择6种(黄连、苦参、连翘、大黄、生地、知母)常用抗菌中药,采用水提法提取浓度至1g/ml。以稀释法测定上述中药对100株临床分离株的最低抑菌浓度(MIC)。结果大黄、黄连、连翅对MRSA有较强抑菌作用,其中以黄连对MRSA的作用最强,MIC值≤0.025g/ml。同一种中药对MRSA的不同菌株表现出相近的抑菌活性。结论常用抗菌中药对MRSA有一定的抑菌作用,在耐甲氧西林金黄色葡萄球菌感染的防治中抗菌中药可以发挥一定作用。
Objective To investigate antibacterial activity of traditional Chinese medicine against methicillin-resisistant Staphylococcus aureu （MRSA）. Methods Six traditional Chinese medicines （Coptis Chinesis etc） were selected and extracted with pure water to make a concoction of 1g/ml. 100 chnicial isolated strains of MRSA were used to determine their minimal inhibitory concentration in vitro with liquid dilution method. Results Three herbs had inhibitory effects on the strain of MRSA with varied extent, among which Captis Chinesis showed the strongest inhibitory effect with a MIC of 0.025g/ ml to MRSA. Furthermore, the inhibitory effect of the same herbal drug was almost the same to different strains of MRSA . Conclusion Some of traditional Chinese medicines is of certain inhibitory effect on MRSA.
出处
《中国热带医学》
CAS
2009年第2期219-220,共2页
China Tropical Medicine
基金
重庆医科大学公共卫生学院大学生科技创新基金资助
关键词
耐甲氧西林金黄色葡萄球菌
药物敏感试验
抗菌作用
最小抑菌浓度
Traditional Chinese Medicine
Methicillin-resisistant Staphylococcus aureu
Antibacterial activity
Minimal inhibitory concentration
