摘要
目的观察清温败毒饮、黄连解毒汤对金黄色葡萄球菌和大肠埃希菌的药理作用。方法对清温败毒饮、黄连解毒汤的水煎提取液进行体外抗菌试验,体外抗菌试验用试管两倍稀释法,观察给药前后清温败毒饮、黄连解毒汤最低杀菌浓度(MBC)示其杀菌活性的变化。结果清温败毒饮对金黄色葡萄球菌的最低抑菌浓度(MIC)为15·6mg/ml,MBC为31·2mg/ml,对大肠埃希菌的MIC为7·8mg/ml,MBC为15·6mg/ml;黄连解毒汤对大肠埃希菌、金黄色葡萄球菌的MIC为15·6mg/ml,MBC为31·2mg/ml。结论清温败毒饮、黄连解毒汤具有抗金黄色葡萄球菌及大肠埃希菌的作用。
OBJECTIVE To evaluate the pharmacological actions of the Formulae of Qinwenbaiduyin and Huanglianjiedutang in antibacterial experiment in vitro, METHODS Test tube method and plating method were employed in antibacterial experiment while test was conducted in antiviral experiment with extract of the Formula by water and then observing the pathological changes in the lungs after medication. RESULTS The minimal inhibirory concentration （MIC） effect of Qinwenbaiduyin was 15.6 mg/ml, the minimal bacteriocidal concentration （MBC） was 31.2mg/ml to Staphylococcus aureus; minimal inhibirory concentration （MIC） effect was 7.6mg/ml. MBC was 15.6mg/ml to Escherichia coll. The MIC effect of Qinwenbaiduyin was 15.6 mg/ml, the MBC was 31.2mg/ml to S. aureus and E. coll. CONCLUSIONS The Formulae of Qinwenbaiduyin and Huanglianjiedutang have antlbacterial effect on S. aureus and E. coli in experiment.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2006年第9期993-994,共2页
Chinese Journal of Nosocomiology
关键词
清温败毒饮
金黄色葡萄球菌
大肠埃希菌
体外抗菌实验
Qinwenbaiduyin
Staphylococcus aureus
Escherichia coli
Antibacterial experiment in vitro
