3Lukas J, Groshen S, Saffari B, et el. WAFI/CIPI gene polymorphysim and expression in carcinomas of the breast, ovary and endometrium. Am J Pathol, 1997;150( 1 ) : 167 -75.
4Hui AM, Kanai Y, Sakamoto M, et al. Reduced p21 WAF1/CIP1 expression and p53 mutation in hepatoeellular careinomas[J].Hepatology, 1997 ; 25 : 575 - 579.
5Furutani M, Arii S, Tanaja H, et al. Decreased expression and rare somatic mutation of the CIP1/WAF1 gene in human hepatocellular carcinoma. Cancer Lett, 1997 ; 111 : 191.
6Haupt Y, Maya R, Kazaz A, et al. MDM2 promotes the rapid degradation of p53[J]. Nature, 1997;387:296-299.
7Momand J, Zambetti GP, Olson DC, et al. The mdm2 oncogene products forms a complex with the p53 protein and inhibits p53 mediated transactivation[J]. Cell, 1992;69:1237-1245.
8Oliner JD, Pietenpol JA, Thiagalingan S, et al. Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53[J].Nature, 1993;362:857-860.
9Skomedal H, Kristensen GB, Abeler VA, et al. TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumors and stage 1 carcinomas[J].J Pathol 1997; 181 : 158 - 165.
10Wakasugi E, Kobaigashi T, Tamaki T, et al, p21 (WAF1/CIP1)and p53 protein expression in breast cancer.Am J Clin Pathol,1997; 107(6) :684--691.
