摘要
报道了吸附阴极溶出伏安法测定异烟肼。探讨了电极反应机理。在０．０１ｍｏｌ／Ｌ硼砂底液中，峰电位为－１．４０Ｖ。峰电流与异烟肼浓度在４．０×１０－７～１．５×１０－５ｍｏｌ／Ｌ范围内呈良好的线性关系，相关系数为０．９９１３。富集６０ｓ检出限为９．０×１０－８ｍｏｌ／Ｌ。该方法用于异烟肼片剂的测定，获得满意结果。
A cathodic stripping voltammetric method for the determination of isoniazide is described.In 0.01mol/L Na 2B 4O 7 solution,isoniazide was accumulated on a glassy carbon electrode in an open circuit for a given period of time .The cathodic stripping peak was found at -1.4V.The second derivative peak height was proportional to the concentration of isoniazide in the range from 4.0×10 -7 ～1 5×10 -5 mol/L.The correlation coefficient was 0.9913.The detection limit was 9.0×10 -8 mol/L with 60s accumulation.This method was applied to determine isoniazide with satisfactory results.The electrode reaction mechanism of isoniazide was also discussed.
出处
《分析试验室》
CAS
CSCD
1998年第1期9-12,共4页
Chinese Journal of Analysis Laboratory
基金
河南省自然科学基金
关键词
异烟肼
玻碳电极
阴极溶出伏安法
雷米封
Isoniazide
glassy carbon electrode
adsorptive stripping voltammetry
