摘要
目的探讨何首乌高温清蒸后泻下成分与泻下作用的关系，为制订制何首乌的质量标准提供依据。方法用紫外分光光度法测定何首乌中两种饮片规格（块0．8～1cm，厚片2—4mm）蒸制过程中的结合型蒽醌含量，观察小鼠服用两种规格制何首乌饮片的泻下作用。结果何首乌块（0．8～1cm）清蒸6h无泻下作用，结合型蒽醌含量为2．09mg／g；何首乌厚片（2—4mm）清蒸4h无泻下作用，结合型蒽醌含量为2．0mg／g。结论何首乌高压蒸制后无泻下作用，结合型蒽醌含量明显降低，可考虑将结合型蒽醌含量作为制何首乌的限定指标。
Objective To find out the relationship between purgative principles and purgative action after Polygonum multiflorum Thunb. was steamed through high -temperature, so to provide a basis for making quality standards. Methods To determine the content of combined anthraquinone of two specifications （ pieces 0.8 - 1 cm, thick slice 2 - 4 mm） in steaming by UV spectro- photographic method and to observe purgative actions of two specifications in rats. Results It was the best to steam 6 hours for piece and 4 hours for thick slice without purgative action and the content of combinated anthraquinone was 2.09 mg/g and 2.00 mg/g respectively. Conclusion There is no purgative action after Polygonum multiflorum Thunb. was steamed, the content of combined anthraquinone are significantly lower, so it can be considered combined -anthraquinone as the limited indication of processed Polygonum multiflorum Thunb..
出处
《时珍国医国药》
CAS
CSCD
北大核心
2008年第11期2654-2655,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(No.30760312)
国家中药现代化科技产业(云南)基地建设专项基金资助(No.2002ZY-11)
关键词
何首乌
结合型蒽醌
泻下作用
Polygonum multiflorum Thunb.
Combined -anthraquinone
Purgative action
