摘要
捕获-再捕获(CR)法在流行病学研究中常用于难以完全计数群体大小的估计。本文简要介绍了CR法应用范围及使用条件:①所研究的群体必须恒定;②捕获和再捕获所获得的两样本之间不应该存在鉴别错误;③样本的独立性是该方法的另一要求;④按CR模式要求群体内的每一个体具有同等机会被捕获和再捕获。并对如何应用CR法估算住院病人ADRs真实发生率及CR法的缺点作一介绍。研究结果显示,CR法在药物流行病学研究中具有可行性。所采用的CR方法估计ADRs发生率,可以提供一条更好的估计ADRs发生率的新途径。
Capture-recapture (CR) has been used in epidemiology for the estimation of the size of population that are difficult to enumerate completely. Presented in this paper are application range of CR and key assumptions of CR method : 1) There is no change to the population during the investigation; 2) There is no loss of tage (individuals can be matched from capture to recapture); 3) The two samples are independent; and 4) For each sample, each individual has the same chance of being included in the sample. The paper describes the application of CR in the estimation of hospitalized patients and its limitations. Our experience showed that CR used for the estimation of ADRs may offer a better way of indentifying te rate of ADRs.
出处
《药物流行病学杂志》
CAS
1997年第2期104-106,共3页
Chinese Journal of Pharmacoepidemiology
