摘要
目的了解上海市静安区大学生麻疹抗体阳性率和抗体水平分布情况,评价大学生麻疹免疫状况,探讨有效的成人麻疹免疫策略。方法以静安区某高校的大一、大二学生为研究对象,用酶联免疫吸附试验(ELISA)对对象的血清麻疹IgG抗体进行检测,并比较不同性别、户籍地、年级学生的麻疹抗体水平。结果麻疹IgG抗体1∶10滴度的阳性率为99.0%(101/102),1∶100滴度的阳性率为35.3%(36/102),不同性别、不同户籍地的学生麻疹抗体水平未见显著性差异,入学时间不同的大一和大二学生麻疹抗体水平存在显著性差异。结论上海市目前对高校入学新生强化免疫麻疹疫苗的策略是切实有效而且必要的,多数学生对麻疹有免疫力,强化免疫并不能长时间维持麻疹抗体的高水平,如何适时对育龄期女性进行麻疹强化免疫尚有待于进一步的探讨。
OBJECTIVE To investigate the level and distribution of measles antibody of undergraduate students in Jing＇an District, Shanghai, and evaluate measles immunity level. Trying to approach available strategy of measles immunization in adults. METHODS The undergraduate students of Grade 1 and Grade 2 in an university were investigated. Measles IgG antibody were detected by Enzyme Linked Immunosorbent Assay （ELISA）. Level of measles antibody were compared between students of different gender, censue register and grades. RESULTS Postive rate of measles IgG antibody of 1：10 dilution is 99.0%（101/102）, while positive rate of 1：100 dilution is 35.3%（36/102）. There was no significant difference of measles antibody level between male and female, and no significant difference be-tween people from Shanghai and other places, but there was significant difference between students of different grades. CONCLUSIONS The present strategy in Shanghai that fresh students of university are all reimmunizated is effective and necessary. Most students are immunizing of measles, but high level of measles antibody can＇t be kept for a long time by reimmunization. When is adequate toreimmunizate for female of child-beating period is still need to be discussed.
出处
《中国初级卫生保健》
2008年第11期35-36,共2页
Chinese Primary Health Care
关键词
麻疹
抗体
免疫
measles, antibody, immunization
