摘要
目的丙泊酚复合麻醉应用于实验犬外科手术,进行效果评价。方法成年健康杂种犬13只,雌雄不限。术前30 min肌内注射阿托品0.5 mg,吗啡10 mg,进行气管插管,静脉注射氯胺酮50 mg,静脉注射丙泊酚首次剂量5 mg/kg体重,维持剂量1 mg/kg。结果丙泊酚复合麻醉,平均麻醉起效时间40 s,首次剂量平均维持17.3min,重复给药平均维持13.6 min,无死亡。丙泊酚有较强的麻醉效果,诱导时间短,起效快,恢复快速平稳,而且无副作用。结论丙泊酚复合麻醉适合于犬的外科手术实验,是一种较为理想的麻醉方法。
Objective To investigate the anesthetic effect of propofol in combination with ketamine in dog surgical experiments.Methods Thirteen healthy dogs were included in the present study,males and females together.0.5 mg atropine and 10 mg morphine were administered intramuscularly 30 min before the experiment.Tracheal intubation,5 mg/kg propofol adopted i.v.at the first time,and the maintenance dose was 1 mg/kg.50 mg katamine administered i.v.before the operation.Results The combined anesthetic reaction time was 40 sec in average.The first injection lasted 17.3 min in average and following injections 13.6 min.None dog died.Propofol had stronger anesthetic effect with a shorter induction time,rapid reaction time,rapid and smooth resuscitation and less adverse effects.Conclusion The propofol combined with katamine anesthesia appears to be a satisfactory method for dogs during surgical operation.
出处
《中国比较医学杂志》
CAS
2008年第10期15-17,共3页
Chinese Journal of Comparative Medicine
