摘要
目的探讨18-35岁中心型肥胖者与QT离散度及ST-T改变的心电学指标的关系。方法对年龄18-35岁的39例单纯性中心型肥胖者（肥胖组）与34例正常体质量者（对照组）进行12导联同步心电图记录及测量QT离散度（QTd）、校正后QT离散度（QTcd）、ST段及T波、血压、体质量指数（BMI）、腰臀比（WHR）。结果肥胖组的BMI、WHR、QTd、QTcd均增大,与对照组比较差异有统计学意义（P〈0.01）,且肥胖组出现ST-T改变的病例中QTd增大更明显。结论年轻中心型肥胖者的QTd增大,尤其是伴有ST-T改变者中QTd增大更显著,提示心肌细胞电生理活动明显异常,并提出心电学指标有可能作为早期预测肥胖者具有较高患心血管病风险的一项参考指标。
Objective To explore the relationship between the central obesity Youth aged from 18 to 35 years old and the electrocardiographic index such as the QT dispersion （QTd） and ST-T changing. Methods To measure the electrocardiogram of 12 leads, QTd, QTed ,ST segment, T wave, blood pressure, body mass index （BMI） and waist-hip ratio （WHR） in 39 patients with central obesity （obesity group） and 34 normal weight healthy subjects （control group） , whose ages are all from 18 to 35 years old. Result The BMI,WHR, QTd, QTcd of the obesity group were higher than the normal group, with a significant difference comparied to the normal group （P 〈 0. 001 ） , and QTd were more larger in the obesity group patients with ST-T changing. Conelusion QTd of the central obesity youth are over the normal reference value, especially QTd of those with ST-T changing increaseing more significantly. The result indicates that the eletrophiological activity of the myocytes is significantly abnormal and the electrocardiographic index would be a reference index which could forecast the risk of the Cardiovascular Disease in obesity.
出处
《中国实用医药》
2008年第27期45-47,共3页
China Practical Medicine
基金
广西科学基金项目课题(桂科基0575041)
