摘要
目的探讨18～35岁年轻人颈动脉内中膜厚度（intima—media thickness，IMT）与血压及QT离散度的关系。方法对107例18～35岁年轻人测量血压、体质量指数（body mass index，BMI），根据BMI将研究对象分为正常体质量组、肥胖组，应用超声对两组年轻人颈动脉进行检测，分析两组间颈动脉IMT与血压及QT离散度的关系。结果与正常体质量组比较，肥胖组血压、IMT、QT离散度增大，差异有统计学意义（P〈0.05）；IMT与收缩压呈直线正相关[左侧颈动脉IMT（LLMT）：r=0．224，P=0．021；右侧颈动脉IMT（RIMT）：r=0．193，P=0．047），与舒张压无明显相关（LIMT：r=0．123，P=0．210；RIMT：r=0．138，P=0．159）；QT离散度D50InS者发生IMT异常的危险度高于QT离散度≤50ms者（OR=6．223，P-40．05）。结论18～35岁年轻人IMT与收缩压呈正相关，QT离散度增大是IMT异常的高危因素，QT离散度〉50ms、收缩压〉120mmHg（1mmHg=0．133kPa）应行IMT检查。
Objective To investigate the relationship between carotid artery intima-media thickness （IMT） and blood pressure（BP） as well as QT dispersion in 18 - 35 young people. Methods Body mass index （BMI） and BP of 107 people in 18 - 35 years of age were measured, the carotid artery was also detected by 2-dimensional and color Doppler ultrasound. According to BMI, all candidates were divided into group A（normal BMI） and group B（obesity）, then the relationship between IMT and BP, QT dispersion were analyzed. Results Compared with group A,BP,IMT,QT dispersion in group B were increased,there was significant diference between the two group （ P 〈0.05）. Relationship was positive correlative between IMT and systolic BP（LIMT： r = 0. 224, P = 0. 021 ;RIMT： r = 0. 193, P = 0. 047） ,but negative correlative between IMT and diastolic BP（I.1MT： r = 0. 123, P = 0. 210; RIMT： r = 0. 138, P = 0. 159）. The risk estimate of abnormal IMT was higher when QT dispersion ）50 ms than that ≤50 ms（OR = 6. 223, P〈0.05）. Conclusions The systolic BP is positive correlative with IMT of carotid artery at age 18-35, increasing QT dispersion is a high risk factor of abnormal IMT. IMT should be detected when QT dispersion 〉50 ms and systolic BP 〉120 mm Hg.
出处
《中华超声影像学杂志》
CSCD
2008年第10期858-860,共3页
Chinese Journal of Ultrasonography
基金
广西壮族自治区科技厅应用基础研究项目资助（桂科基0575041）
关键词
超声检查
颈动脉
内中膜厚度
肥胖症
Uhrasonography
Carotid arteries
Intima-media thickness
Obesity
