摘要
目的探讨晚期COPD急性加重期的临床特点、发病机制及防治措施。方法对已出院的病例临床资料及文献进行复习。结果135例患者伴有肝功能损害46例,均为COPD晚期,在感染等诱因作用下急性加重,出现心功能衰竭、呼吸衰竭和高碳酸血症。其中感染、缺氧、心衰和呼衰是导致肝功能损害的主要原因,且在病程中又互为因果。结论控制感染、纠正缺氧、治疗心衰、改善通气可缓解病情,受损肝功能可以大部分得到缓解。
[Objective] To explore the clinical characteristics, the etiology, the mechanism and prevention of advanced chronic obstructive pulmonary disease at acute aggravated phase. [Methods] To review the clinical data of the discharged patients and the literature. [Results] 46 patients with damaged liver functions out of 135 patients all indicate advanced chronic obstructive pulmonary disease, and appear heart failure, respiratory failure as well hyper-capnia through motivation of infection or something at acute aggravated duration. Among these reasons, infection, hypoxia, heart failure and respiratory failure are main reasons which resulted damages on liver functions, moreover, to be affected mutually in the course of diseases. [Conclusions] Condition may be relieved and liver function damage also may be relieved mostly by controlling infection, rectifying hypoxia, treating heart failure, improving ventilation.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2008年第19期2869-2870,2873,共3页
China Journal of Modern Medicine
关键词
慢性阻塞性肺疾病
肝功能
chronic obstructive pulmonary disease
liver functions
