5Pauwels RA, Buist AS, Calverley, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Golbal Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med, 2001, 163(5) :1256.
6Welgus HG, Jeffrey JJ, Eisen AZ. The collagen substrate specificity of human skin fibroblast. J Biol Chem, 1981,256(18):9511.
7Tozzi CA, Christiansen DL, Poiani GJ, et al. Excess collagen in hypertensive pulmonary arteries decrease vascular distensibility. Am J Respir Crit Care Med, 1994, 149(5):1317.
8Durmowicz AG,Parks WC, Hyde DM, et al. Persistence reexpression and induction of pulmonary arterial fibronection, tropoelastin and type Ⅰ procollagen mRNA expression in neonatal hypoxic pulmonary hypertention. Am J Pathol,1994, 145(6):1411.
6Sehindl M, Sehoppmann SF, Samonigg H, et al. Over expression of hypoxia-indueible faetor lalpha is associated with an unfavorable prognoses in lymph node positive breast cancer[ J ]. Clin Cancer Res,2002,8 ( 6): 1831-1837.