摘要
目的分析服用药物期间饮酒对机体造成的损害。方法通过典型病例介绍了服药期间乙醇在体内的异常代谢和"双硫仑样反应"。结果"双硫仑样反应"可造成机体乙醛中毒,服药后饮酒还可使体内酪胺大量蓄积、加重肝毒性、神经系统抑制等,并可降低药物的中毒极限量使人更易中毒。其相关药理反应可引起消化道出血、血压升高、脑溢血、肝坏死等严重并发症和危急重症。结论服药后饮酒可对机体造成严重损害。
Objective To analyze the injury to the human body induced by the alcohol drinking when the drugs are used. Methods The abnormal metabolism and the Disulfirom-like reaction of the ethanol in the human body when the drugs were used were analyzed by introducing the typical cases. Results The Disulfirom-like reaction could induce the acetaldehyde poisoning. The alcohol drinking when the drugs were used could make the tyramine accumulated in the human body, worsen the liver toxicity and inhibit the nervous system, and lower the minimal toxic dose. The pharmaceutical reaction induced the severe complications and critical diseases including the hemorrhage of the digestive tract, the increase of the blood pressure, the brain hemorrhage and the liver necrosis. Conclusion The alcohol drinking after the drug are used can cause severe injury to human body.
出处
《中国疗养医学》
2008年第11期688-689,共2页
Chinese Journal of Convalescent Medicine
关键词
药物
饮酒
双硫仑反应
Medicine
Alcohol drinking
Disulfirom-like reaction
