期刊文献+

USPIO MR增强检查在脊椎骨髓炎模型感染区巨噬细胞活性检测中的应用 被引量:4

Macrophage activity in infected areas of an experimental vertebral osteomyelitis model: USPIO-enhanced MR imaging-feasibility study
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摘要 目的前瞻陛研究超小超顺磁性氧化铁(uhrasmall superparamagnetic iron oxide,USPIO)MR增强检查在实验性兔脊椎骨髓炎动物模型感染区巨噬细胞活性检测中的应用价值。方法10只实验动物兔的椎间盘(实验水平)内注入细菌建立腰椎体骨髓炎模型,同时向另一椎间盘(对照水平)注射生理盐水。平均间隔12d后给予USPIO。并在注射前和注射后24h后行MRI检查。MR成像序列包括T1WI自旋回波(SE),T2WI快速自旋回波(FSE),T2*梯度回波序列(GRE)。将MRI与组织学表现(巨噬细胞免疫染色和普鲁士蓝染色)对照分析。
出处 《国际医学放射学杂志》 2008年第5期390-390,共1页 International Journal of Medical Radiology
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参考文献8

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二级引证文献11

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