摘要
目的调查湖北省气传花粉的种类及飘散规律.探讨其与花粉症的关系。方法 2003年11月～2004年10月在湖北省16个城区选点,同时进行气传花粉的调查,并对2 300例花粉症患者进行花粉过敏原皮肤试验及发病季节分析,对其中352例蒿属花粉过敏症患者进行气道反应性测定,并分析其与花粉浓度问的相关性。结果全年观察到花粉种类61种,收集花粉257 520粒。气传花粉飘散高峰集中在春季的3～4月和秋季的8～10月。花粉症患者的发病季节与气传花粉高峰期相吻合.反映气道反应性的使一秒钟用力呼气容积降低20%所需乙酰甲胆碱的累积量(PD20-FEV1)与气传花粉浓度呈显著负相关(r=-0.6829,P<0.05)。结论本调查为湖北省气传花粉的流行病学研究提供了参考资料,对本地区与花粉相关的过敏性疾病的防治具有重要的临床指导意义。
Objective To study the genera and seasonal distribution of airborne pollen in Hubei province, and its relationship with pollinosis. Methods From November 2003 to October 2004, an airborne pollen investigation was performed in 16 chosen cities and counties of Hubei province using gravity sedimentation technique. Meanwhile, univalent skin prick tests of pollens and the study of invasion season were performed on 2 300 patients with pollenosis. Among them, 352 cases underwent the airway responsiveness measure- ments, and the correlation between airway responsiveness and results of pollen count was analyzed. Results A total of 61 pollen genera were observed and 257 520 pollens were collected. The airborne pollen peak duration each year occurred in two seasons： spring （March and April） and autumn （from August to October）. The attack of pollinosis corresponded to pollen peak duration. There was a significantly negative relationship between the provocative dose causing a 20% decrease of forced expiratory volume in one second （FEV1） from baseline （PD20-FEV1） and airborne pollen concentration （r=-0.6829, P 〈 0.05）. Conclusion The study provides useful information for airborne pollen epidemiology of Hubei province. It provides important insights to clinical prevention, diagnosis and treatment of pollen related allergic diseases.
出处
《中华临床免疫和变态反应杂志》
2007年第1期22-26,共5页
Chinese Journal of Allergy & Clinical Immunology
基金
湖北省卫生厅科研基金(LJ200220)
关键词
湖北省
气传花粉
花粉症
气道反应性
Huboi province
airborne pollen
pollinosis
airway responsiveness
