摘要
目的采用随机、双盲、药物对照的方法观察腰痛灵栓治疗腰椎间盘突出症对患者腰部和下肢各位点微循环的影响,探讨其部分作用机理。方法将63例腰椎间盘突出症患者随机分为腰痛灵栓治疗组(33例)和消炎痛栓对照组(30例),观察治疗前及治疗后15d,患者腰部和下肢各位点微循环的变化情况。结果两组治疗前后患侧下肢拇趾关节、二三趾间位点微循环比较差异均有显著意义(P<0.05);两组治疗前后腰部各位点、患侧下肢膝上5cm位点微循环比较差异无统计学意义(P>0.05)。结论腰痛灵栓对腰部的微循环改善不明显,对下肢微循环有明显的改善作用,其微循环的改善可能与神经功能的恢复存在相关性。
Objective To observe clinical effect of Yaotonglin suppository on LDP（ lumbar intervertebral disc protrusion） patients＇ waist and lower extremity＇ s microcirculation by randomized, double - blinded and positive drugs controlled methods. Discuss its partial functional mechanism. Methods 63 LDP patients were randomly assigned to Yaotonglin suppository group（33 cases） and Xiaotonglin suppository group（30 cases）. The changes of LDP patients＇ s microcirculation on waist and lower limbs were observed before and after each treatment for 15 days. Results There was significant difference between pre and post treatment （ P 〈 0.05） of each group＇ s microcirculation change on the affected side hallux joint and the part between second and third toe. However, there was no difference between pre and post treatment （ P 〉0.05） of each group＇ s microcirculation change on the waist and the point which is 5cm above knee at the affected side. Conclusion By using Yaotonglin suppository, little improvement could be found on waist microcirculation but much improvement on the lower limb. The improvement of microcirculation might have certain relationship with neural function recovery.
出处
《中国微循环》
北大核心
2008年第4期228-231,共4页
Journal of Chinese Microcirculation
基金
国家中医药管理局资助项目(04-05LL11)
关键词
腰痛灵栓
腰椎间盘突出症
微循环
Yaotonglin suppository
LDP（ lumbar intervertebral disc protrusion）
Microcirculation
