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Toll样受体9配体CpG寡核苷酸在特异性免疫治疗中的作用 被引量：3

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摘要 变应性疾病的变应原特异性免疫治疗开始于1911年，是目前惟一能够影响变应性鼻炎自然进程的治疗手段。经过一个世纪的临床实践，特异性免疫治疗日臻完善，尤其是标准化变应原疫苗在特异性免疫治疗中的应用和推广，大大降低了急性超敏反应等并发症，同时在临床上取得了令人满意的疗效。但目前特异性免疫治疗还面临着一些需要解决的问题。首先，免疫接种后急性超敏反应虽然被限制在极低的水平，但仍有个别病例发生。
作者 朱学伟 朱冬冬 董震
机构地区 吉林大学中日联谊医院耳鼻咽喉头颈外科
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2008年第7期546-548,共3页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金 国家自然科学基金（30772409） 卫生部重点学科资助项目 吉林省科技发展项目
关键词 特异性免疫治疗 TOLL样受体9 CPG寡核苷酸 变应原疫苗 配体 临床实践 超敏反应 变应性疾病
分类号 R686 [医药卫生—骨科学]
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参考文献20

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二级参考文献8

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共引文献6

同被引文献40

  • 1赵宇,C.Andrew vanHasselt,吴港生,黄约爱,梁传余,梁秉中.卵白蛋白经鼻致敏建立变应性鼻炎动物模型[J].中华耳鼻咽喉头颈外科杂志,2005,40(3):176-180. 被引量：53
  • 2张罗,韩德民.变应性鼻炎治疗的进展[J].中华耳鼻咽喉头颈外科杂志,2005,40(3):230-232. 被引量：86
  • 3王成硕,张罗,韩德民,王向东,赵岩,周兵,刘健慧.标准化尘螨变应原疫苗治疗变应性鼻炎一年的疗效和安全性研[J].中国耳鼻咽喉头颈外科,2007,14(1):3-6. 被引量：62
  • 4孙臻峰,孟晴虹,董频.变应性鼻炎和哮喘患者变应原类型及免疫治疗疗效的比较[J].中国耳鼻咽喉头颈外科,2007,14(1):11-13. 被引量：5
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引证文献3

二级引证文献16

中华耳鼻咽喉头颈外科杂志
2008年 第7期

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