摘要
目的观察大黄对降糖通脉颗粒治疗肾衰作用的影响。方法在甘油复制肾衰模型大鼠上,分别给予含大黄的降糖通脉颗粒和不含大黄的降糖通脉颗粒,测定给药后动物尿中蛋白和血清BUN、CR含量。结果2种降糖通脉颗粒均能明显降低尿中蛋白含量,但对血清BUN、CR含量的降低作用,含大黄降糖通脉颗粒明显优于不含大黄组。结论大黄对降糖通脉颗粒改善肾衰指标,具有重要意义。
OBJECTIVE To observe the effect of Radix et Rhizoma Rhei in the treatment of renal failure with Jiangtang Tongmai Granule. METHOD .liangtang Tongmai Granule with Radix et Rhizoma Rhei and without Radix et Rhizoma Rhei was given respectively to renal failure rat models and followed by determination of the content of protein, serum BUN and CR in the animal urine. CONCLUSION Both kinds of granules could markedly reduce the content of urine protein, but the granule with Radix et Rhizoma Rhei had better effect in reducing serum BUN and CR. CONCLUSION Radix et Rhizoma Rhei is of important significance in improving renal failure indexes.
出处
《南京中医药大学学报》
CAS
CSCD
2008年第4期280-282,共3页
Journal of Nanjing University of Traditional Chinese Medicine
关键词
大黄
降糖通脉颗粒
肾脏
毒性
Radix et Rhizoma Rhei
Jiangtang Tongnmi Granule
kidney
toxicity
