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TLR4介导的信号转导通路的相关阻断研究与炎症性肠病 被引量：3

Inhibitor researches on TLR4 signal transduction pathways and inflammatory bowel disease
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摘要 炎症性肠病发病机制尚不明确,研究发现TLR4(Toll样受体4)介导的信号通路在炎症性肠病发病机制中起着重要作用。目前已有较多阻断此通路的研究报道,抑制此通路的关键环节或关键分子以避免过强的炎症反应已成为众多学者研究的新方向,此文对此作了概括总结。 At present the exact mechanism of IBD is still remain unidentified. However, it is considered to be related to abnormal immunity, Nowadays, many researches on TLR4 signal transduction pathways are carried out, which offers a new opportunity to the treatment of IBD.
作者 王磊 刘懿
机构地区 复旦大学附属华山医院消化科
出处 《国际消化病杂志》 CAS 2008年第3期220-223,共4页 International Journal of Digestive Diseases
关键词 炎症性肠病 TOLL样受体4 NF-ΚB MAPK Inflammatory bowel disease TLR4 NF-κB MAPK
分类号 R574 [医药卫生—消化系统]
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参考文献18

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同被引文献25

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国际消化病杂志
2008年 第3期

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