摘要
目的探讨垂体柄阻断综合征的MRI表现及与临床意义的相关性。资料与方法14例MRI诊断的垂体柄阻断综合征患儿，男13例，女1例，年龄5～16岁，平均（11±3）岁，对其影像及临床资料进行回顾性分析。结果垂体柄缺如6例，其中多种腺垂体激素缺乏4例，单一生长激素缺乏2例；垂体柄变细8例，其中单一生长激素缺乏7例，多种腺垂体激素缺乏1例。14例均表现为垂体后叶异位，13例表现为垂体前叶发育不良。结论垂体柄缺如或明显变细，垂体后叶异位，垂体前叶发育不良是垂体柄阻断综合征的MRI三联征，垂体后叶异位是提示垂体柄阻断综合征的特征性标志。目前，MRI是诊断垂体柄阻断综合征的唯一可靠的影像学检查方法。
Objective To investigate the MRI characteristics of pituitary stalk interruption syndrome （PSIS） and the correlation with growth hormone deficiency（GHD）. Materials and Methods MR images and clinic data of fourteen cases with PSIS [male 13 ,female 1 ; 5 to 16 years old, mean age （ 11 ±3） years] were retrospectively reviewed. MRI images were acquired before and after the injection of gadolinium. Results The pituitary stalks were absent in 6 cases （ group A）. 4 cases in group A demonstrated multiple pituitary hormone deficiencies （MPHD） and the other 2 were isolated growth hormone deficiencies （IGHD）. The pituitary stalks showed marked thinning in 8 cases （group B）. 7 cases in group B demonstrated MPHD and only one case was IGHD. All the 14 cases identified ectopic bright signals of posterior pituitary lobe located at the median eminence except one in the middle of the stalk. Thirteen of 14 associated with hypoplasia of the anterior pituitary. The height of anterior pituitary in group A was significantly smaller than that of in group B （ P 〈 0.01 ）. Conclusion The triad of PSIS by MRI are （ 1 ） absence or marked thinning of pituitary stalk. （2） ectopic posterior pituitary （EPP）. （3） hypoplasia of the anterior pituitary. EPP is a typical feature of PSIS. Magnetic resonance imaging is an unique and reliable method for identifying PSIS.
出处
《临床放射学杂志》
CSCD
北大核心
2008年第6期821-824,共4页
Journal of Clinical Radiology
关键词
垂体柄阻断综合征
垂体后叶异位
磁共振成像
Pituitary stalk interruption syndrome Ectopic posterior pituitary Magnetic resonance imaging
