期刊文献+

血脑屏障的研究方法在中医药中的应用及思考 被引量:4

Application and Thingking of Research Methods of Blood-Brain Barrier in Traditional Chinese Medicine
暂未订购
导出
摘要 血脑屏障(BBB)是维持中枢神经系统内环境稳定的结构基础,现代医学对BBB主要的研究方法有:BBB超微结构的观察,色素伊文思蓝、金属镧或者放射性核素等示踪剂,CT、MRI等影像学观察,体外模型,特定指标等。简介现代医学BBB主要的研究方法在中医药学中的应用,并作述评。借鉴现代医学血脑屏障的研究手段,为从多方面研究中医药对血脑屏障的影响提供方法学,有助于中医理论研究、中药归经研究、阐明中医药及针灸的作用机制等。 The blood - brain barrier (BBB) is the specialized system, which ensures proper function of the central nervous system. Many methods, such as microscopy and tracer (Evans blue, lanthanum, radionuclide, et al) , imageology (CT, MRI) , in vitro model, several biochemical indicatrix are applied to investigate the morphous and function of blood - brain barrier in western medicine. To introduce the main methods that are used to measure the role of the traditional Chinese medicine(TCM) in BBB, The role of TCM in BBB would be better discovered depending on the development of new methodologies of BBB, which will be helpful to illuminate scientifically the theory of TCM and mechanisms of TCM and acupuncture.
出处 《中华中医药学刊》 CAS 2008年第6期1289-1292,共4页 Chinese Archives of Traditional Chinese Medicine
关键词 血脑屏障 中医药 研究方法 Blood - Brain barrier traditional Chinese medicine research methods
  • 相关文献

参考文献26

二级参考文献180

共引文献462

同被引文献69

  • 1刘树民,刘学伟,姚素媛,刘天宇.龙胆碱对高热惊厥模型大鼠海马区神经元损伤的保护作用研究[J].中医药学报,2009,37(6):11-13. 被引量:8
  • 2刘瑜,胡文立,宋爱利,刘国贞,许兰萍,卢玲巧,杨慧,董小黎.大鼠脑血栓模型的实验研究[J].实用医学杂志,2005,21(18):1992-1993. 被引量:20
  • 3王品,李庆龙,田建生,张宗保,石俊英.脑脉舒胶囊的药效学试验研究[J].齐鲁药事,2007,26(2):116-118. 被引量:2
  • 4过伟峰.关于中医内科脑病学科建设的思考[J].中医杂志,2007,48(1):75-76. 被引量:10
  • 5高学敏.中药学[M].北京:中国中医药出版社,2008:1.
  • 6Wu SN,Jan CR, Li HF,et al. Stimulation of large-conduct- ance Ca2+ activated K + channels by Evans blue in cul- tured endothelial cells of human umbilical veins [ J ]. Bio- chem Biophys Res Commun,2009:254(3 ) :666.
  • 7Yang Y,Rosenberg GA.Blood-brain barrier breakdown in acute andchronic cerebrovascular disease[J].Stroke,2011,42(11):3323-3328.
  • 8Brambrink AM,Evers AS,Avidan MS,et al.Ketamine一induced neuroapoptosis in the fetal and neonatal rhesus macaque brain[J].Anesthesiology,2012,116(2):372-384.
  • 9Jin ZL,Gao N,Dan Z,et al.The extracts of Fructus Akebiae,a preparation containing 90%of the active ingredient hederagenin:Serotonin,norepinephrine and dopamine re-uptake inhibitor[J].Pharmacol Biochem Behav,2012,100(3):431-439.
  • 10Thomalla G, Sobesky J, KtihrmannM, et al. Two tales : hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is re- lated to severity and duration of ischemia : MRI study of acute stroke pa- tients treated with intravenous tissue plasminogen activator within 6 hoursEJ]. Stroke, 2007,38(2) :313.

引证文献4

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部