摘要
目的:探讨肝癌患者与正常健康人及化疗前后血小板4项参数的变化和临床意义。方法:用Sysmex,SE-9000全自动血液分析仪对正常健康人、肝癌患者及化疗前后血小板数(PLT)、血小板平均体积(MPV)、血小板分布宽度(PDW)、大血小板比率(P-LCR)4项参数进行检测并比较。结果:肝癌患者PLT结果低于正常对照组,MPV结果高于正常对照组(P<0.05),差异有统计学意义。PDW、P-LCR结果明显高于正常对照组(P<0.01),差异有统计学意义。肝癌患者化疗后PLT、MPV、PDW、P-LCR结果均明显低于化疗前(P<0.01),差异有统计学意义。结论:血小板参数的检测可作为肝脏受损程度,肝癌疗效及预后判断的参考指标。
Objective：To investigate the changes and clinical significance of 4 platelet parameters in liver cancer. Mcthod：PLT count, MPV, PDW and P-LCR of patients suffered from liver cancer were detected by Sysrnex, SE-9000 automatic blood analysis instrument, and these results were compared with that of normal group. Result： PLT count of liver cancer group was obviously less than that of normal group, while MPV was higher than that of normal group （P〈0.05）. PDW and P-LCR of liver cancer group were obviously higher than those of normal group（P〈0.01）. After chemotherapy, PLT count, MPV, PDW and P-LCR were all lower than those before chemotherapy （ P〈0. 01 ）. Conclusion：It would be of some significance to detect the 4 parameters of platelet in judging the damage degree of liver, therapeutic effect and prognosis of liver cancer patients.
出处
《临床血液学杂志（输血与检验）》
CAS
2008年第3期307-308,共2页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
肝癌
血小板4项参数
化疗
Liver cancer
4 Platelet parameters
Chemotherapy
