摘要
目的探讨肝病患者红细胞平均体积(MCV)、红细胞体积分布宽度(RDW)、血小板的4项参数变化与病情的关系。方法应用ABBOTT公司生产的CD-1600全自动血细胞分析仪检测181例肝病患者和100例健康者为对照组。结果(1)肝硬化组、慢乙肝组、急性肝炎组MCV、RDW、MPV均显著高于对照组(P<0.01),PLT、PDW、PCT均显著低于对照组(P<0.01);(2)MCV、RDW、MPV之间成正相关关系,PLT、PDW、PCT之间亦成正相关关系,MCV、RDW、MPV与PLT、PDW、PCT之间成负相关关系。结论(1)MCV、RDW可以反映肝病病情的轻重和肝功能损害程度;(2)血小板4项参数测定为肝病患者血小板功能的初步评价提供了简便、快速、可靠的方法。
Objective To study the relation of the changes in MCV,RDW and4parameters of platelets in patients with hepatitis to the course of disease.Methods One hundred and eighty one patients with hepatitis and100healthy controls were detected by a CD-1600automatic blood cell counter from ABBOTT company.Results The MCV,RDW and MPV in patiets with hepatic cirrhosis,chronic hepatitis,and acute hepatitis were significantly higher than those in the controls(P<0.01).Meanwhile,PLT,PDW and PCT in these patients were significantly lower than those in the controls(P<0.01).The MCV,RDW and MPV were positively correlated,so were PLT,PDW and PCT.The MCV,RDW,MPV and PLT,PDW,PCT were negatively correlated.Con-clu sions (1)The MCV and RDW can reflect the severity of hepatic disease and dam-age of liver function.(2)The determination of4blood platelet parameters provides a easy,rapid,and reliable way for primary assessment of blood platelet function the pa-tients with liver diseases.
出处
《江西医学检验》
2002年第4期201-202,232,共3页
Jiangxi Journal of Medical Laboratory Sciences
