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肝病患者早期MCV、RDW及血小板4项参数测定的临床意义 被引量:16

Clinical significent of changes within MCV,RDW and 4 indexes platelet parameters of patients with hepatitis disease in early stage
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摘要 目的 探讨肝病患者红细胞平均体积 (MCV)、红细胞体积分布宽度 (RDW )、血小板的 4项指数变化与病情的关系。方法 应用Coulter公司JT—IR全自动血液计数仪检测 181例肝病患者和 10 0例健康者为对照组。结果  ( 1)肝硬化组、慢乙肝组、急性肝炎组MCV、RDW、MPV均显著高于对照组 (P <0 .0 1) ,PLT、PDW、PCT均显著低于对照组 (P <0 .0 1) ;( 2 )MCV、RDW、MPV之间成正相关关系 ,PLT、PDW、PCT之间亦成正相关关系 ,MCV、RDW、MPV与PLT、PDW、PCT之间成负相关关系。结论  ( 1)MCV、RDW可以反映肝病病情的轻重和肝功能损害程度 ;( 2 )血小板 4项参数测定为肝病患者血小板功能的初步评价提供了简便、快速。 Objectives To study the relationship of the changes within MCV,RDW and the blood platelet parameters of the hepatitis in the early stage.Methods 181cases with hepatitis disease was detected by a JT type auto blood cell counter made in COULTER company. 100cases without detectable diseases as controls. Results MCV,RDWand MPV in hepato cirrhosis group,chronic hepatitis group,and acute hepatitis group were higher than those in control,there were obviously significant ( P <0.01). Meanwhile,PLT,PDWand PCT in these groups were lower than that in control( P <0.01).The relationship among MCV,RDWand MPV is positive.Otherwise,that between MVC,RDW,MPVand PLT,PDW,PCT is negative. Conclusions (1)The bank of clinical manifestation and injury of liver function can be deflected by MCVand RDW.(2)The detection of 4 blood platelet parameters provides a easy,rapid, reliable way as initial comment of the patients blood platelet function.
出处 《宁夏医学杂志》 CAS 2000年第7期385-386,共2页 Ningxia Medical Journal
关键词 肝疾病 平均血小板体积 血小板体积分布宽度 Liver diseases RDW PLT MPV PDW
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