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透明细胞肉瘤诊断与治疗 被引量:7

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摘要 透明细胞肉瘤是一种少见的软组织恶性肿瘤,目前在其病理学和分子生物学特点、临床特征及治疗等方面仍存在争议。其组织学和免疫组化特性与恶性黑色素瘤十分相似,但目前通过分子生物学方法已可将两者区分。虽然透明细胞肉瘤生长缓慢,影像表现类似良性肿瘤,但复发率和转移率很高。早期诊断和正确处理是治疗透明细胞肉瘤的关键。多数学者认为早期肿瘤经完整手术切除联合术后放疗可降低局部复发率,是目前较好的治疗选择。但是对淋巴结清扫及化疗作用还存在诸多争议,许多患者化疗效果令人失望。新的化疗方案和生物免疫治疗在透明细胞肉瘤治疗中有一定的前景,但还需进一步临床研究加以证实。
作者 张亮 陈统一
出处 《国际骨科学杂志》 2008年第2期89-90,共2页 International Journal of Orthopaedics
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参考文献18

  • 1Meis-Kindblom JM. Clear cell sarcoma of tendons and aponeuroses: a historical perspective and tribute to the man behind the entity. Adv Anat Pathol, 2006; 13 (6) : 286- 292.
  • 2Patel RM, Downs-Kelly E, Weiss SW, et al. Dual-oolor, break-apart fluores cence in situ hybridization for EWS gene rearrangement distinguishes clear cell sarcoma of soft tissue from malignant melanoma. Mod Pathol, 2005; 18(12): 1585-1590.
  • 3Garcia JJ, Kramer MJ, Mackey ZB, et al. Utility of CD117 immunoreactivity in differentiating metastatic melanoma from clear cell sarooma. Arch Pathol Lab Med, 2006; 130(3):343-348.
  • 4Panagopoulos I, Mertens F, Debiee-Rychter M, et al. Molecular genetic characterization of the EWS/ATF1 fusion gene in clear cell sareoma of tendons and aponeuroses. Int J Cancer, 2002; 99(4):560-567.
  • 5Panagopoulos I, Mertens F, Isaksson M, et al. Absence of mutations of the BRAF gene in malignant melanoma of soft parts (clear cell sarcoma of tendons and aponeuroses). Cancer Genet Cytogenet, 2005; 156(1):74-76.
  • 6Kawai A. Hosono A, Nakayama R, et al. Clear cell sarcoma of tendons and aponeuroses: a study of 75 patients. Cancer, 2007; 109(1) :109-116.
  • 7Dim DC. Cooley LD, Miranda RN. Clear cell sareoma of tendons and aponeuroses: a review. Arch Pathol Lab Med, 2007; 131(1):152-156.
  • 8Malchau SS, Hayden J, Hornicek F, et al. Clear cell sarcoma of soft tissues. J Surg Oncol, 2007; 95(6):519-522.
  • 9Finley JW, Hanypsiak B, McGrath B, et al. Clear cell sarcoma: the Roswell Park experience J Surg Oncol, 2001; 77( 1 ) : 16-20.
  • 10Sara ,AS. Evans HL, Benjamin RS. Malignant raelanoma of soft parts (dear cell sarcoma), A study of 17 cases, with emphasis on prognostic factors. Cancer, 1990; 65(2):367-374.

同被引文献35

  • 1虞聪,徐建光,劳杰,陈德松,陈亮,顾玉东.上肢软组织恶性肿瘤的手术治疗和预后[J].中华手外科杂志,2004,20(2):75-76. 被引量:15
  • 2邢汝维,方志伟,宋金纲,杨蕴,马育林,张瑾,陈勇,滕胜,多健.透明细胞肉瘤的治疗及疗效分析[J].中华骨科杂志,2005,25(8):485-490. 被引量:5
  • 3嵇学仙,方铣华,程晔.软组织透明细胞肉瘤5例临床病理分析[J].临床与实验病理学杂志,2005,21(6):746-747. 被引量:8
  • 4丁宜,孟淑琴.透明细胞肉瘤的病理诊断与鉴别诊断[J].中国骨肿瘤骨病,2005,4(5):267-269. 被引量:3
  • 5Enzinger FM. Clear-cell sarcoma of tendons and aponeuroses: an analysis of 21 cases. Cancer, 1965,18: 1163-1174.
  • 6Takahira T, Oda Y, Tamiya S, et al. Alterations of the pl6INK4a/P14ARF pathway in clear cell sarcoma. Cancer Sci, 2004,95:651-655.
  • 7Kawai A, Hosono A, Nakayama R, et al. C 1 ear cell sarcoma of tendons and aponeuroses: a study of 75 patients. Cancer, 2007,109:109-116.
  • 8武忠弼 杨光华主编.中华外科病理学[M].北京:人民卫生出版社,2002.646.
  • 9Enzinger FM. Clear-cell sarcoma of tendons and aponeuroses. Ananaly- sis of 21 cases[J].Caneer, 1965, 18:1163-1174.
  • 10Chung EB, Enzinger FM. Malignant melanoma of soft parts:a reassess- ment of clear cell sarcoma[J].Am J Surg Pathol, 1983,7:405 - 413.

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