摘要
测定长沙地区５９３名成年人的血浆脂蛋白（ａ）［Ｌｐ（ａ）］水平。结果表明：Ｌｐ（ａ）水平程偏态分布，对数转换可使其分布正态化。２０９例冠心病患者中，血浆Ｌｐ（ａ）水平＞１００ｍｇ．Ｌ－１者占该组的３４．８％，而在３０５名正常对照组者中仅占１７．３％（Ｐ＜０．０１）。冠心病组的Ｌｐ（ａ）水平亦显著高于正常对照组。多因素逐步回归分析发现血浆Ｌｐ（ａ）水平与冠心病呈正相关。提示血浆Ｌｐ（ａ）水平与冠心病发病密切相关，是冠心病重要的独立危险因素。
The plasma lipoprotein(a) levels were determined among 593 adults in Changsha city, Hunan province. The result showed that the distribution of Lp(a) levels in all the individuals was a skewness which can be normalized by data transformation into logarithm. Plasma Lp(a) concentration>300mg·L -1 was 34.8% in 209 subjects with coronary artery disease (CAD) and 17.3% in 305 health controls (P<0.01). The Lp(a)levels were significantly higher in subjects with CAD than in health controls. Multiple regression stepwise analysis found that Lp(a) levels were positively correlated with CAD. This study indicates that plasma levels of Lp(a) are strongly related to CAD and may be an important independent risk factor for CAD.
出处
《湖南医科大学学报》
CSCD
1997年第4期320-322,共3页
Bulletin of Hunan Medical University
关键词
脂蛋白类
成人
冠心病
coronary artery disease
lipoproteins
adults
