摘要
本研究对69例皮下埋植避孕者根据阴道出血类型不同分为月经规则组、月经紊乱组、闭经组，并对其分别进行生殖激素测定，监测卵泡生长发育及宫颈评分。结果表明：埋植期间月经规则组除黄体期P水平较正常对照组降低外（P＜0．01），其它生殖激素均在正常范围内波动；月经紊乱组及闭经组P和E2低于正常对照组黄体期，相当于正常对照组卵泡期低水平。B超监测卵泡表现三种类型：1．卵泡逐渐成熟并排卵；2．卵泡逐渐长大并在整个周期内持续存在；3.卵泡未发育。研究结果提示黄体功能不足是皮下埋植避孕的作用机理之一，并说明皮下埋植者月经失调和生殖激素及卵泡发育特征之间的变化与LNG的抑制有关，研究结果进一步证实皮下埋植剂具有高效、安全的优点，对扩大推广应用皮下埋植避孕法起到指导作用。
survey of reproductive hormones, ovarian follicles'development and cervical mucus score was carried out in 69 women with Norplant. They were devided into 3 groups with normal menstruation,abnormal menstruation and amenorrhea according to the bleeding type and the women with Norplant being taken out served as a control group. The results showed that during the period of using Norplant,all types of reproductive hormones in the normal menstruation group varied within the normal extent except P in luteal phase was lower than that in the control group. The P and E2 level in abnormal menstruation and amenorrhea groups,was similar to that in the control group in follicular phase,but lower in luteal phase. Three kinds of ovarian folliclesby were observed B-mode ultrasonography:1. Ovarian follicles were growing up and ovulated. 2. Ovarian follicles were becoming larger and larger but no ovulation. 3. Ovarian follicles did not develop.The result illustrates that the lake of function of corpus luteum is the one of the mechanisms that is used with Norplant,and also indicates that abnormal menstruation reproductive hormone level and ovarian follcle growth in women with Norplant are relevance to the inhibition of LNG. So Norplant has been testified to be a safe and effective, and will find a wide use
出处
《生殖与避孕》
CAS
CSCD
北大核心
1997年第4期218-222,共5页
Reproduction and Contraception
关键词
埋植剂
雌二醇
孕酮
超声监测
排卵
Implant, Estradiol (E_2), Progesterone(P), Ultrasonography, Ovulation
