摘要
12只SD大鼠被随机分为对照组和实验组．在低压氧舱内模拟8000m高空飞行，来探讨高空飞行对大鼠血浆、淋巴细胞、肝脏中主要热应激蛋白（HSPs）——HSP27和HSP70水平的影响。结果发现与对照组相比，实验组大鼠血浆HSP27含量明显增高（P＜0．01），而HSP70含量略微增高，但无显著性差异（P＞0．05）；大鼠淋巴细胞HSP27、HSP70均明显增加，但以HSP70含量增加更为明显（P＜0．01），大鼠肝脏HSP27、HSP70均显著增加，具有极显著性差异（P＜0．01）。这些结果提示HSP27、HSP70在抗低压缺氧中可能有一定的作用．
12 SD rats were randomly divided into control and exposed groups. Effects of simulated flightat low atmospheric pressure on the main heat strees protein--HSP27 and HSP70 of rats'plasma,lymphocytes and liver were studied. The results revealed that compared with the controls,rats'plasma HSP27 in exposed group was significantly increased (P < 0. 01 ), however, plasmaHSP70 was only slightly increased without significant difference (P>0. 05). HSP27 and HSP70 ofboth lymphocyte and liver were significantly increased. These results indicated that HSP27' andHSP70 might play some roles in antagonism to low oxygen caused by low atmospheric pressure.
出处
《工业卫生与职业病》
CAS
CSCD
1997年第2期69-71,共3页
Industrial Health and Occupational Diseases
