摘要
目的探讨血浆胆固醇水平与人体健康的关系。方法以1475例住院患者为研究对象,测定血浆总胆固醇和血浆白蛋白水平;采用24小时回顾法调查营养摄入量;对血浆胆固醇水平增高、正常和降低时的疾病谱情况,营养摄入的方式及血浆白蛋白的水平进行比较;并对临床常用营养制剂的胆固醇含量进行调查。结果住院患者中,低和高胆固醇血症的发生率无显著性差异(12.1%vs.11.4%,P>0.05)。低胆固醇血症组中男性的比例显著高于女性(67%vs.33%,P<0.05)。低胆固醇血症患者的肺部疾病和精神障碍的发生率显著高于高胆固醇血症和正常胆固醇者(P<0.05)。低胆固醇血症患者能量、蛋白质和胆固醇的摄入量显著低于高胆固醇血症患者(P<0.05)。低胆固醇血症患者采用肠内、肠外营养治疗的比例显著高于高胆固醇血症和正常胆固醇者(P<0.05),血浆白蛋白水平与高胆固醇血症和正常胆固醇者无显著性差异。临床常用肠内外营养制剂不含或含少量胆固醇。结论应重视对住院患者低胆固醇血症的防治。引起低胆固醇血症的主要可能原因是采用肠内、肠外营养治疗及患者胆固醇的摄入量过低。
Objective To investigate the relationship between hypocholesterolemia levels and human health. Methods Totally 1475 hospitalized patients were enrolled. Their plasma cholesterol and albumin levels were determined, and their nutrition intakes were investigated by 24-hour diet retrospective survey. Disease onsets, nutritional supply mode, and plasma albumin levels were compared among patients with hypocholesterolemia, normal plasma cholesterol surveyed. , and hypercholesterolemia. Cholesterol contents in the commonly used nutrition support products were Results The incidences of hypocholesterolemia and hypercholesterolemia were not significantly different （12. 1% vs. 11.4%, P 〉0. 05）. Hypocholesterolemia were more commonly seen in men （67% in men vs. 33% in women, P〈0. 05）. The morbility of respiratory diseases and spirit dysfunction in hypocholesterolemia group were significantly higher than those in hypercholesterolemia group and normal plasma cholesterol group respectively （ P 〈 0. 05 ）. The intakes of energy, protein, and cholesterol in hypocholesterolemia group were signifi- cantly lower than those in hypercholesterolemia group （ P 〈 0. 05 ）. The ratio of adopting enteral or parenteral nutritional therapy in the hypocholesterolemia was significantly higher than those in the other groups （ P 〈 0. 05 ）. Plasma albumin levels were not significantly different among three groups. Cholesterol contents was zero or minimal in the commonly used enteral or parenteral nutritional products. Conclusions Prevention and treatment of hypocholesterolemia is important in hospitalized patients. The potential mechanisms of hypocholesterolemia may include insufficient cholesterol intake and the application of enteral/parenteral nutritional therapies.
出处
《中国临床营养杂志》
2008年第1期22-25,共4页
Chinese Journal of Clinical Nutrition
关键词
低胆固醇血症
呼吸道疾病
营养治疗
调查与分析
hypocholesterolemia
respiratory diseases
nutritional therapy
survey and analysis
